

A team of space marines known as the Rapid Response Tactical Squad, led by Sarge, is sent to a science facility on Mars after somebody reports a security breach. There, they learn that the alert came after a test subject, a mass murderer purposefully injected with alien DNA, broke free and began killing people. Dr. Grimm, who is related to team member Reaper, informs them all that the chromosome can mutate humans into monsters -- and is highly infectious.
Practical Effects
The FPS sequence — a 4-minute first-person shooter homage that's pure camp genius
Acting
Dwayne Johnson going full unhinged villain, eating scenery like protein powder
Production
Czech Republic standing in for Mars with maximum corridor reuse

Director
Andrzej Bartkowiak
Trivia, insights & behind the scenes
The famous 4-minute first-person sequence was shot in 14 days using a custom camera rig built to mimic the game's perspective.
This bombed so hard it killed video game movies for years, yet somehow predicted The Rock's eventual heel-turn charisma in later blockbusters.