Dick Bannister is the new field boss of the Ford Logging Company, a Canadian logging-crew during a time when conflicts with the powerful Consolidated Lumber Company, a bitter rival company, have turned bloody, like a private war. His boss, Miss Edith Ford, comes to inspect the lumberjack camp, bringing her doctor fiancé with her. Dick is attacked by his rivals and left for dead. His loss of blood is so great that he needs a transfusion, but no human will volunteer, so the surgeon uses a wolf as a source of the blood. Afterwards, Dick begins having dreams where he runs with a pack of phantom wolves, and the rival loggers get killed by wolves. Soon, these facts have spread through the camp. (via YouTube)
Practical Effects
Actual wolves on set, zero CGI, maximum unpredictability.
Direction
Dual directors somehow made this coherent-ish.

Director
George Chesebro
Trivia, insights & behind the scenes
This is widely considered the earliest surviving werewolf feature film, predating Universal's Wolf Man by sixteen years.
The 'wolf blood transfusion' plot device reflects 1920s anxiety about blood science and eugenics—literally fear of 'corrupted' bloodlines.